Colivet 4.8


Each 1 g contains:

Colistin Sulphate           4.8 MIU

Treatment and metaphylaxis of gastrointestinal infections caused by non-invasive Escherichia coli susceptible to Colistin.

The presence of the disease in the herd should be established before metaphylactic treatment.

Administered orally via drinking water or milk (replacer)


Calves and Lambs: 100,000 IU of Colistin / Kg bodyweight (1 g of Colivet 4.8  / 48 kg bodyweight) daily for 3-5 consecutive days.


Poultry and Turkey: 75,000 IU of Colistin / Kg bodyweight (1 g of Colivet 4.8  / 64 kg bodyweight) daily for 3-5 consecutive days.



For the administration through the drinking water, the exact daily amount of Colivet 4.8  should be calculated, according to the following formula:

(mg Colivet 4.8  / kg body weight / day  X  mean bodyweight (kg) of animals to be treated) / (Mean daily water consumption (liter / animal)) = mg Colivet 4.8  / liter of drinking water.


To prepare the stock solution, place the indicated quantity of Colivet 4.8   in a 10 liter container, fill with water and stir until dissolved. The maximum recommended concentration is 250 grams of Colivet 4.8   / 10 liters of drinking water and 500 mg of Colivet 4.8   / liter of milk (replacer).


The medicated water should be the only source of drinking water for the animals for the entire duration of the treatment period.


-Do not use in case of hypersensitivity to Colistin.

-Do not use in case of resistance to the polymyxin.

-Do not use in horses, particularly in foals, since Colistin, due to a shift in the gastrointestinal microflora balance could lead to the development of antimicrobial associated colitis (Colitis X), typically associated with Clostridium difficile, which may be fatal.

-In the case of newborn animals and of animals with severe gastrointestinal and renal disorders the absorption of colistin may be increased. Neuro- and nephrotoxic alterations may occur.

Meat and offal: Calves, Lambs, Poultry and Turkey: 1 day

Eggs: Zero days.

Not authorised for use in animals producing milk for human consumption.

Store in a dark place at a temperature below 30oC.